ORDER DENYING TRANSFER

SARAH S. VANCE, Chair.

Before the Panel:* Plaintiffs in two actions (Beard and Courtney) pending in the Southern District of Indiana move under 28 U.S.C. § 1407 to centralize 41 actions in that district.1 The actions, which are listed on the attached Schedule A, are pending in a total of 22 districts. Plaintiffs in the other 39 actions did not respond to the motion. Common defendant Eli Lilly and Company (Lilly) opposes centralization.

I.

The complaints in these 41 personal injury actions are substantially similar. Plaintiffs allege that they suffered a wide variety of withdrawal symptoms — including, inter alia, "brain zaps," memory lapses, suicidal thoughts, increased anxiety, stomach cramping, insomnia, nausea, and dizziness — after discontinuing use of Cymbalta, a Lilly prescription drug used to treat depression, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. Plaintiffs contend that at all relevant times, Lilly has known or should have known of the significantly increased risk of withdrawal symptoms posed by Cymbalta, but has failed to warn of that risk adequately.

This litigation is before us for a second time. At our December 2014 hearing session, we denied a motion for centralization of 25 Cymbalta cases (eighteen of which also are included in the present motion). See In re: Cymbalta (Duloxetine) Prods. Liab. Litig. (Cymbalta I), 65 F.Supp.3d 1393 (J.P.M.L. 2014). At the time of the denial, we also were aware of 21 other related federal actions. See id. at 1393 n.1. As now, Lilly opposed centralization.

In our Cymbalta I decision, we acknowledged that these actions "share factual issues concerning Cymbalta's development, marketing, labeling, and sale," id. at 1393, but concluded that centralization was not warranted for a number of reasons. First, the procedural posture of the actions "varie[d] significantly." Id. For example, whereas in the two earliest-filed of the cases, the discovery cutoff was quickly approaching, the more recently filed actions were "still in their infancy." Id. at 1394. Second, the record showed "that most, if not all common discovery ha[d] already taken place in th[e] earlier-filed actions." Id. Lilly already had produced nearly two million pages of documents, as well as corporate representatives for Rule 30(b)(6) depositions in the areas of drug safety, sales training, and labeling. Id. Third, only a limited number of plaintiffs' counsel were involved in the litigation. Id. Just two firms represented plaintiffs in all of the 25 constituent actions, and Lilly was represented by only one law firm. Id.

II.

On the basis of the papers filed and the hearing session held, we deny plaintiffs' motion, as there has been no "significant change in circumstances" in the litigation since our decision in Cymbalta I.2 All the factors that weighed against centralization then still are present today. These 41 cases are at substantially different procedural stages. For example, although eighteen of the cases were commenced in August 2014, the eight actions in the Southern District of Indiana all were brought just this year, and do not have scheduling orders.3 In contrast, the Middle District of Florida Krupp action has a discovery cutoff of February 5, 2016; the Middle District of Alabama Moss action has a cutoff of March 25, 2016; and the Southern District of California Wheeler has a cutoff of April 29, 2016.

Common discovery has advanced even further since Cymbalta I. Indeed, in recent months, four Cymbalta cases have gone to trial — including two cases in the Central District of California that were on the Section 1407 motion in Cymbalta I. According to Lilly, it has produced nearly three million pages of documents; Lilly witnesses have sat for four 30(b)(6) depositions covering such topics as the company's regulatory affairs, sales training, clinical trial, and safety surveillance functions; and there have been seven fact depositions of current and former Lilly employees involved with the development, clinical trials, and post-marketing surveillance of Cymbalta withdrawal trials. Lilly represents that it has made this common discovery available to all plaintiffs in cases in which discovery has been served on Lilly and protective orders have been entered, and that it will make that discovery available to all plaintiffs in the same manner. Although moving plaintiffs complain that discovery has been conducted in an uncoordinated manner and that Lilly's production has been deficient in several respects, the current record even more firmly supports our conclusion in Cymbalta I that "the discovery that has occurred to date has been substantial." See 65 F. Supp. 3d at 1394.

Finally, the record does not show a significant increase in the number of unique counsel. Plaintiffs in these actions are represented by one or more of four law firms, and Lilly is represented in virtually all actions by the same law firm. Given this limited number of involved counsel, informal coordination and cooperative efforts by the parties and involved courts remain practicable.4 See, e.g., In re: Eli Lilly & Co. (Cephalexin Monohydrate) Patent Litig., 446 F.Supp. 242, 244 (J.P.M.L. 1978); see also Manual for Complex Litig., Fourth, § 20.14 (2004).

IT IS THEREFORE ORDERED that the motion for centralization of these actions is denied.

SCHEDULE A

Middle District of Alabama

MOSS, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 3:14-01135

Central District of California

PATTERSON, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 2:14-08527 CAPORALE, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 5:14-01662 HOLLOWELL, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 5:14-01663 BARRETT, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 5:14-01675 O'SHEA, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 8:14-01274

Eastern District of California

CHESHIER v. ELI LILLY AND COMPANY, C.A. No. 1:14-01265 WOODRUFF, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 2:14-01890 NELSON-DEVLIN, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 2:14-02811 BEN, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 2:14-02914 WOLFF, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 2:14-03004

Southern District of California

WHEELER, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 3:14-01882

District of Colorado

CHENEY, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:14-02249 MARTIN v. ELI LILLY AND COMPANY, C.A. No. 1:14-02800

Middle District of Florida

LAICA-BHOGE, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 6:14-01286 VALENTINO v. ELI LILLY AND COMPANY, C.A. No. 6:14-01816 KRUPP, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 8:14-02792 BROTHERTON v. ELI LILLY AND COMPANY, C.A. No. 8:14-02876

Northern District of Georgia

COUCH v. ELI LILLY AND COMPANY, ET AL., C.A. No. 1:14-02564

Southern District of Indiana

HILL, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:15-00141 BOLES ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:15-00351 DECRANE, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:15-00365 BICKHAM, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:15-00531 COURTNEY, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:15-00643 WASHINGTON, ET AL. v. ELI LILLY AND COMPANY., C.A. No. 1:15-00700 JONES, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:15-00701 BEARD, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:15-00922

Western District of Louisiana

FAIRBANKS v. ELI LILLY AND COMPANY, ET AL., C.A. No. 1:14-02469

District of Maine

ORLANDO, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:14-00438

District of Maryland

BOLING, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 8:14-02554

District of Minnesota

McCABE v. ELI LILLY AND COMPANY, ET AL., C.A. No. 0:14-03132

Northern District of Mississippi

SPEARMAN, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 1:15-00006

District of Nevada

WALKER v. ELI LILLY AND COMPANY, C.A. No. 2:14-01988

District of New Hampshire

CARPENTER, ET AL. v. ELI LILLY AND COMPANY, ET AL., C.A. No. 1:14-00540

Eastern District of North Carolina

WILLIAMS, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 5:14-00460

Middle District of North Carolina

HARRIS v. ELI LILLY AND COMPANY, ET AL., C.A. No. 1:14-00682

Western District of Pennsylvania

ROSSERO, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 2:14-01084

Eastern District of Tennessee

EDENS, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 3:14-00491

Southern District of Texas

PORKORNY, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 4:14-02960

Eastern District of Washington

WAGNER, ET AL. v. ELI LILLY AND COMPANY, C.A. No. 2:14-00270

Western District of Wisconsin

STREETER v. ELI LILLY AND COMPANY, C.A. No. 3:14-00555