The quick answer is that if you want your wife to move out of the house, the first thing you will probably need to do is file for divorce. That is, unless you can come to some separation agreement that provides for her to move out and seek her own place to live.
As for a more detailed answer, you have not given much information to go on. Many other facts will be needed to give you sound advice, e.g., how long you have been married, whether you have children, whether your wife has worked during the marriage, etc. These and many other matters could factor into the answer to your question. You should consult with a lawyer to determine the appropriate next steps.